Meales IgG/IgM Rapid Test

Meales IgG/IgM Rapid Test

Type: Uncut Sheet

Brand: Bio-mapper

Catalog:RT0711

Specimen:WB/S/P

Sensitivity:99.70%

Specificity:99.90%

Measles virus is the pathogen of measles, which belongs to the measles virus genus of paramyxovirus family. Measles is a common acute infectious disease in children. It is highly infectious and is characterized by skin papules, fever and respiratory symptoms. If there is no complication, the prognosis is good. Since the application of live attenuated vaccine in China in the early 1960s, the incidence rate of children has decreased significantly. However, it is still a major cause of child mortality in developing countries. After the extinction of smallpox, WHO has listed measles as one of the infectious diseases planned to be eliminated. In addition, subacute sclerosing panencephalitis (SSPE) was found to be related to measles virus.


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Typical measles cases can be diagnosed according to clinical symptoms without laboratory examination. For mild and atypical cases, microbiological examination is required to confirm the diagnosis. Because the method of virus isolation and identification is complex and time-consuming, which requires at least 2-3 weeks, serological diagnosis is often used.
Virus isolation
The blood, throat lotion or throat swab of the patient at the early stage of the disease were inoculated into human embryonic kidney, monkey kidney or human amniotic membrane cells for culture after being treated with antibiotics. The virus proliferates slowly, and typical CPE can appear after 7 to 10 days, that is, there are multinucleated giant cells, acidophilic inclusions in cells and nuclei, and then the measles virus antigen in the inoculated culture is confirmed by immunofluorescence technology.
Serological diagnosis
Take double sera of patients in acute and convalescent periods, and often perform HI test to detect specific antibodies, or CF test or neutralization test. The clinical diagnosis can be assisted when the antibody titer is more than 4 times higher. In addition, indirect fluorescent antibody method or ELISA can also be used to detect IgM antibody.
rapid diagnosis
Fluorescent labeled antibody was used to check whether there was measles virus antigen in the mucous membrane cells of the patient’s throat rinse at catarrhal stage. Nucleic acid molecular hybridization can also be used to detect viral nucleic acid in cells.

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